NAD+ (1000mg)

Metabolism
NAD+ (1000mg)
Price range: $99.99 through $749.93 Sale!
In Stock

Earn up to 750 Points.

NAD⁺ (nicotinamide adenine dinucleotide) is an essential cellular coenzyme that plays a central role in redox metabolism and energy production. It functions as a key electron carrier, cycling between NAD⁺ and NADH to support mitochondrial oxidative phosphorylation and glycolytic energy transfer in experimental models. Beyond metabolism, NAD⁺ acts as a required substrate for sirtuins and PARP enzymes, which are involved in DNA repair, gene expression, cellular stress response, and aging-related pathways. As a result, NAD⁺ is widely used in research focused on mitochondrial health, muscle metabolism, neuroprotection, cellular resilience, and longevity mechanisms.

NOX Guarantee

Every NØX product is released through a controlled quality framework verifying identity, purity, consistency, endotoxin levels, and heavy metal content. Each batch undergoes analytical testing to confirm peptide composition prior to distribution, including independent laboratory verification using chromatographic and mass spectrometry methods. Only batches that pass internal quality review and release authorization enter circulation, reflecting our commitment to rigorous testing, documentation, traceability, and the continuous pursuit of uncompromising quality.

Lab Reports

Freedom Diagnostics
Freedom Diagnostics
Avg Purity: 99.95%
Avg Mass: 1025.12mg
Result Date: June 15, 2026
Search Code: NØXP2606110686
Lot: NXND-01K

Rated by verified customers

4.9
Based on 2,000+ verified reviews

Customer review

(4)
5.0/5
5 4
4 0
3 0
2 0
1 0
  1. NovaFit Bootcamp

    June 25, 2026 ✔ Verified owner

    I’ve purchased and taken NAD + from NOX for 4 months and I will not be myself without it. I consistently have energy and zeal. I’m very motivated to be active and I don’t get exhausted easily. The change was drastic and immediate in 24 hours. I wear an Oura ring to track my sleep cycles. I have had increased frequency of good sleep quality compared to sleep quality prior to NAD+. I’m sold!

  2. Craig Junneau

    July 27, 2026 ✔ Verified owner

    I’ve been taking NAD for 30+ days now. I noticed the first week an extreme hightened level of energy, less pain and lots of stamina at work. I remember stopping one day and sitting with myself and reflecting…like wow I feel so good. How can I possibly feel this good? I’m so grateful for NAD+. I got to believing in NAD and its put positive energy on my health. NOX’s NAD was more pure than other sources i get it from. Its more yellow which is what its supposed to be

  3. Yusef Mo

    August 8, 2026 ✔ Verified owner

    NOX NAD+ was my pick, helped my memory, focus, and I even felt I had more energy throughout the day.

  4. JourneyWithPeptides

    August 17, 2026 ✔ Verified owner

    I’m currently using 100mg twice per week (so 200mg weekly). I started at 25mg twice per week and doubled it until I got to 100mg. I would say by week three I really noticed the shift in energy and I could tell when I hadn’t taken any.

    Its as evident as being angry when youre hungry and you know you havent eaten haha.

Add A Review

Description

NAD⁺ (Nicotinamide Adenine Dinucleotide) is an essential cellular coenzyme present in every living cell and fundamental to energy metabolism, cellular repair, and stress resilience. It plays a dual role as both an electron carrier in metabolic reactions and a required substrate for key regulatory enzymes involved in longevity and DNA maintenance.

1. Supports Cellular Energy Production

One of the most critical benefits of NAD⁺ is its role in energy generation. NAD⁺ cycles between its oxidized (NAD⁺) and reduced (NADH) forms to drive mitochondrial oxidative phosphorylation and glycolysis, enabling cells to efficiently convert nutrients into ATP. This process is central to maintaining cellular vitality and metabolic performance.

2. Enhances Mitochondrial Function and Health

Healthy mitochondria are essential for overall cellular function. NAD⁺ supports mitochondrial homeostasis, helping maintain efficient electron transport and metabolic flexibility. Research commonly uses NAD⁺ to study mitochondrial efficiency, biogenesis, and stress adaptation, especially under conditions of metabolic demand.

3. Activates Sirtuins Linked to Longevity

NAD⁺ is a required cofactor for sirtuins, a family of enzymes involved in gene regulation, metabolic balance, and cellular longevity. Sirtuin activity has been closely associated with aging research, caloric restriction pathways, and improved cellular stress resistance.

4. Supports DNA Repair and Genomic Stability

NAD⁺ serves as a substrate for poly(ADP-ribose) polymerases (PARPs), enzymes responsible for DNA damage detection and repair. Adequate NAD⁺ availability is essential for maintaining genomic integrity, particularly in cells exposed to oxidative or environmental stress.

5. Promotes Cellular Stress Resilience

Cells rely on NAD⁺ to respond effectively to oxidative stress, inflammation, and metabolic challenges. Through its involvement in redox balance and enzyme activation, NAD⁺ helps regulate cell survival pathways and adaptive stress responses.

6. Supports Muscle Metabolism and Physical Performance Research

NAD⁺ is widely studied in muscle metabolism due to its role in ATP production and mitochondrial efficiency. Research models explore how NAD⁺ availability influences muscle endurance, recovery signaling, and metabolic flexibility.

7. Plays a Role in Neuroprotection Research

Neurons are highly energy-dependent and sensitive to metabolic disruption. NAD⁺ is commonly investigated in neurobiology research for its potential role in neuronal energy balance, synaptic maintenance, and resistance to cellular stress.

8. Central to Aging and Longevity Research

NAD⁺ levels naturally decline with age, which has linked it closely to aging biology. Research involving NAD⁺ focuses on understanding how restoring or maintaining NAD⁺ levels may support cellular resilience, metabolic health, and age-related functional decline.

9. Regulates Cellular Redox Balance

As a core redox coenzyme, NAD⁺ helps maintain the balance between oxidation and reduction within cells. Proper redox balance is essential for enzyme function, metabolic signaling, and protection against oxidative damage.

10. Essential Tool in Metabolic and Cellular Research

Due to its central role in metabolism, signaling, and repair, NAD⁺ is a cornerstone molecule in studies of mitochondrial biology, energy regulation, stress response, and systems-level cellular health.

Summary

In research contexts, NAD⁺ is valued for its benefits related to energy production, mitochondrial health, DNA repair, stress adaptation, neuroprotection, muscle metabolism, and aging-related pathways. Its involvement in both metabolic and regulatory processes makes it one of the most important molecules for understanding cellular resilience and longevity mechanisms.

Lyophilized (freeze-dried) peptides should be stored in a refrigerator at 2–8°C (36–46°F). For long-term storage, they should be kept in a freezer at -20°C (-4°F) or below. Once reconstituted, peptides must be stored in a refrigerator at 2–8°C (36–46°F) and should not be left at room temperature for extended periods.

Add 5mL of bacteriostatic water to get a solution that is 200mg/mL, such that every 0.1mL (10 units on an insulin syringe) is equal to 20mg of NAD+.

Guaranteed Results
Manufactured under strict quality standards to ensure reliable performance and consistent research outcomes.
Secure Payment
Protected payment systems safeguard every transaction to provide a safe and seamless checkout experience.
Customer Service
Our responsive support team is available to assist with inquiries and provide reliable guidance whenever needed.
Fast Shipping
Orders are processed promptly and shipped through trusted carriers to ensure timely, secure, and dependable delivery.
NAD+ (1000mg)
NAD+ (1000mg)
Add to cart

People Also Bought